Extra Super Tadarise vs. Other ED & PE Meds: Full Comparison

Oct, 21 2025

Quick Takeaways

• Extra Super Tadarise combines tadalafil (a PDE5 inhibitor) and dapoxetine (a short‑acting SSRI) to target both erectile dysfunction (ED) and premature ejaculation (PE) in one pill.
• Onset is about 30‑45 minutes, with erectile support lasting up to 36 hours; dapoxetine works within 1‑2 hours for ejaculation control.
• Compared with standard ED drugs (e.g., sildenafil, vardenafil) it offers a longer window but may have higher cost and a broader side‑effect profile.
• For men who need only ED treatment, single‑ingredient tadalafil or sildenafil remain cheaper and well‑tolerated.
• Always check for contraindications (e.g., nitrates, severe cardiac disease) and discuss with a doctor before starting any combination therapy.

When you search for an all‑in‑one solution for both Extra Super Tadarise is a combination tablet that pairs tadalafil and dapoxetine to address erectile dysfunction and premature ejaculation together. The promise is simple: one pill, two problems solved. But how does it stack up against the more familiar stand‑alone options? This guide walks through the science, the practicalities, the price tag, and the safety considerations so you can decide if the combo is right for you or if a traditional alternative fits better.

How the Combo Works

Tadalafil is a long‑acting phosphodiesterase‑5 (PDE5) inhibitor. By blocking the PDE5 enzyme, it keeps cyclic guanosine monophosphate (cGMP) levels high, allowing smooth muscle in the penis to stay relaxed and blood to flow in. The result is an erection that can be achieved with sexual stimulation. Because tadalafil’s half‑life is around 17.5 hours, its effect can last up to 36 hours, earning it the nickname “the weekend pill.”

Dapoxetine is a short‑acting selective serotonin reuptake inhibitor (SSRI). Unlike typical antidepressant SSRIs that stay in the system for weeks, dapoxetine peaks in the bloodstream within 1‑2 hours and clears in about 6 hours. The brief rise in serotonin helps delay ejaculation without causing the long‑term sexual side effects associated with other SSRIs. When taken together, the two agents aim to keep the penis firm while extending the time before climax.

Side‑by‑Side Comparison

*Prices are average online retail rates in the United States (October 2025) and may vary by pharmacy.

Deep Dive Into Each Alternative

Sildenafil (Viagra) was the first oral ED drug to hit the market in 1998. It blocks PDE5 like tadalafil but has a shorter half‑life, giving a narrower window of opportunity. If you only need occasional support, sildenafil’s lower price and well‑known safety profile make it a solid pick. However, it provides no help with premature ejaculation.

Vardenafil (Levitra) offers a slightly faster onset than sildenafil and similar duration. Some users report fewer visual disturbances. Like sildenafil, it does not address PE.

Avanafil (Stendra) is the newest PDE5 inhibitor, marketed for its rapid onset-some men feel effects in as little as 15 minutes. Its side‑effect rate is modest, but the cost is higher than generic options.

Generic Tadalafil (Cialis) mirrors the long‑acting profile of Extra Super Tadarise’s tadalafil component but lacks any dapoxetine. It’s ideal for men who want flexibility for spontaneous intimacy over a whole day or weekend.

Dapoxetine alone is approved in many countries specifically for premature ejaculation. It’s taken 1‑2 hours before sex and works for a few hours. Men who are satisfied with separate ED treatment often pair dapoxetine with a standard PDE5 inhibitor.

Safety, Contraindications, and Drug Interactions

Both tadalafil and dapoxetine share a major red flag: they must never be combined with nitrates (e.g., nitroglycerin) because the sudden drop in blood pressure can be life‑threatening. Other cautions include severe heart failure, uncontrolled hypertension, and recent stroke.

Common side effects for the combo mirror those of its parts-headache, flushing, and dyspepsia are most frequent. Dapoxetine can add nausea, dizziness, or insomnia, especially if taken on an empty stomach. Because the combination is newer, long‑term data beyond three‑year post‑marketing studies are limited.

Always review current medications. Alpha‑blockers (used for prostate issues), certain antifungals, and macrolide antibiotics can boost plasma levels of either component, increasing side‑effect risk.

Pricing, Availability, and Insurance

Extra Super Tadarise is typically sold as a prescription medication in online pharmacies and specialty clinics. In the United States, it is not covered by most public or private insurers because it combines two drugs that are reimbursable separately. The out‑of‑pocket cost per tablet ranges from $45 to $55, which translates to roughly $135‑$165 for a typical 3‑tablet monthly supply.

By contrast, generic tadalafil and sildenafil are widely covered and can be found for $10‑$15 per tablet at many retail chains. Dapoxetine’s coverage varies; some European plans include it, while U.S. insurers often label it as “off‑label” for PE.

For patients who travel or live in regions where the combo isn’t approved, buying a single‑ingredient PDE5 inhibitor plus a separately prescribed dapoxetine may be more practical.

Choosing the Right Option for You

Ask yourself these three questions:

1. Do I need both ED and PE treatment simultaneously? If yes, a combo like Extra Super Tadarise removes the hassle of taking two pills at different times.
2. Is cost a primary factor? If you’re price‑sensitive, pairing generic tadalafil (or sildenafil) with dapoxetine can save $20‑$30 per month.
3. Do I have health conditions that restrict PDE5 inhibitors or SSRIs? If you have heart disease, uncontrolled hypertension, or are on nitrates, any of these drugs (including the combo) may be unsafe.

When the answer to #1 is “yes” and you have no contraindications, the combo provides convenience and a longer therapeutic window. If you only need occasional ED support, stick with a single‑ingredient PDE5 inhibitor. If premature ejaculation is your main concern, dapoxetine alone may be enough.

Bottom Line

Extra Super Tadarise is a niche product that fills a specific gap: treating two common male sexual issues with one tablet. It shines for men who want the freedom of a “weekend pill” plus ejaculation control without juggling separate meds. Yet its higher price, limited insurance coverage, and a broader side‑effect profile mean it isn’t the default choice for every patient.

Talk to a urologist or qualified health professional, weigh the pros and cons listed above, and decide whether the convenience outweighs the cost. Whatever you choose, the most important step is a candid conversation with your doctor to ensure safety and effectiveness.